Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans

Marcangeli, V., Cefis, M., Hammad, R., Granet, J., Leduc-Gaudet, J.-P., Gaudreau, P., Aubertin-Leheudre, M., Belanger, M., Robitaille, R., Morais, J. A. et Gouspillou, G. (2025). Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans. Aging Cell . Article e70191. ISSN 1474-9718 1474-9726 DOI 10.1111/acel.70191

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Résumé

ABSTRACT
Taurine deficiency was recently proposed as a driver of aging in various species, including humans. To test this hypothesis, we assessed whether circulating taurine was associated with aging and physical performance in 137 physically inactive and physically active men aged 20–93. No association between circulating taurine levels and age, muscle mass, strength, physical performance, or mitochondrial function was observed, thereby challenging the implication of taurine deficiency as a primary driver of aging in humans.

Type de document:	Article
Mots-clés libres:	Aging biomarker Functional capacities Geroscience Mitochondria Mitochondrial function Physical activity Sarcopenia Skeletal muscle Taurine
Date de dépôt:	17 sept. 2025 17:42
Dernière modification:	17 sept. 2025 17:42
Version du document déposé:	Version officielle de l'éditeur
URI:	https://depot-e.uqtr.ca/id/eprint/12243

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